Product Description
Imported Orlistat Weight Loss Capsules Orligal Orlistat Prescription Medication
Weight: 75g
Specifications: 120mg/capsule; 84 capsules/box;
Orligal Orlistat Weight Loss Capsules
Active ingredient per capsule: Orlistat 120mg
The color used for the capsule shell is approved.
Pharmacological Action:
Orlistat is a potent, specific, and reversible long-acting inhibitor of lipases. It exerts its therapeutic activity in the gastric lumen and small intestine by forming a covalent bond with the serine residue of the active site of gastric and pancreatic lipases. The inactivated enzyme is thus unable to hydrolyze dietary fat in the form of triglycerides into absorbable free fatty acids and monoglycerides. As undigested triglycerides are not absorbed, the resulting caloric deficit may have a positive effect on weight control.
Indications:
Orlistat is indicated for weight management, including weight loss, weight maintenance, and prevention of weight regain in adults with an initial body mass index (BMI) of 30 or greater.
Orlistat should be used in conjunction with a mildly hypocaloric, low-fat diet.
Dosage: The recommended adult dose is 120mg (one capsule) three times daily, taken during or up to one hour after each main meal containing fat.
Patients should be on a nutritionally balanced, mildly hypocaloric diet that contains approximately 30% of calories from fat. The diet should be rich in fruits and vegetables. Daily intake of fat, carbohydrate, and protein should be distributed over three main meals. No dose adjustment is necessary for the elderly.
Contraindications:
Orlistat capsules are contraindicated in patients with chronic malabsorption syndrome, cholestasis, and in patients with known hypersensitivity to orlistat or to any of the excipients.
Warnings and Precautions:
In studies up to 4 years, the majority of patients had normal levels of vitamins A, D, E, and K and beta-carotene. To ensure adequate nutrition, the use of a multivitamin supplement should be considered.
The possibility of gastrointestinal events may increase when orlistat is taken with a diet high in fat (e.g., in a 2000-calorie diet, >30% of calories from fat, which is >76 grams of fat). Daily fat intake should be distributed over three main meals. If orlistat is taken with any meal very high in fat, the possibility of gastrointestinal effects may increase. If a meal is missed or contains no fat, the dose of orlistat should be omitted.